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Stem Cell

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Stem Tech's Stem Enhance Increase Stem Cell Circulation Throughout the Body

Medical researchers and scientist increasingly agree that the more stem cells you have circulating in your bloodstream, the greater your health. Stem Enhance is a patented, concentrated extract of Aphanizomenon flos-aquae, a wild aquatic food. A triple blind study confirms that it causes a 25-30% increase in circulating stem cells within 60 minutes.

What is Stem Enhance?
StemEnhance is a
breakthrough, natural botanical extract that supports wellness by helping your body maintain healthy stem cell physiology. It is the very first product on the market from the latest phytoceutical product category called "stem cell enhancers"

 

DESCRIPTION

Cardiovascular Revascularization Medicine (CRM) is an international and multidisciplinary journal that publishes original laboratory and clinical investigations related to revascularization therapies in cardiovascular medicine.

Cardiovascular Revascularization Medicine publishes articles related to preclinical work and molecular interventions, including angiogenesis, cell therapy, pharmacological interventions, restenosis management, and prevention, including experiments conducted in human subjects, in laboratory animals, and in vitro. Specific areas of interest include percutaneous angioplasty in coronary and peripheral arteries, intervention in structural heart disease, cardiovascular surgery, congenital heart disease, coronary heart disease, epidemiology, genetics, health services and outcomes research, invasive imaging, molecular cardiology, preventive cardiology, and vascular medicine.

Cardiovascular Revascularization Medicine will consider all articles describing clinical trials and translational research (ie, those that unite the clinic with the laboratory). The Journal publishes original articles, rapid communications, reviews, technical notes, teaching editorials, and special features. Original articles that address any aspect of cardiovascular revascularization medicine are invited. Letters to the Editor and interesting images are encouraged.

Click photo for Medical Study

STEM ENHANCE 

What is it? 
Stem Enhance is a breakthrough, natural botanical extract that supports wellness by helping your body maintain healthy stem cell physiology. It is the very first product on the market from the latest phytoceutical product category called “stem cell enhancers”.
 
What are stem cell enhancers?
Recent scientific developments have revealed that stem cells derived from the bone marrow, travel throughout the body, and act to support optimal organ and tissue function. Stem cell enhancers are products that support the natural role of adult stem cells.

Why do I need this product?
As you age, the number and quality of stem cells that circulate in your body gradually decrease, leaving your body more susceptible to injury and other age-related health challenges. Just as antioxidants are important to protect your cells from “free radical” damage, stem cell enhancers are equally important to support your stem cells in maintaining proper organ and tissue functioning in your body.

Gabrielle G.. Florida:
Once Gabrielle began taking StemEnhance® , she "more than believed... I knew it" was a miracle. She had been fighting recurring discomfort from a physical trauma that left her one side nearly paralyzed, and she had been in constant discomfort for five months, when she decided to "saturate my body with StemEnhance® ." Taking two capsules every four hours that first day, she was stunned when 95% of her discomfort disappeared overnight! " I will always take StemEnhance® every four hours," Gabrielle says, noting that the average person can enjoy the power of StemEnhance® with two to four capsules daily.


Marjorie L. S., New Mexico:
If you met Marjorie, you would never guess that she's 60 or that she's suffered for years from very poor vision (extreme astigmatism and extreme presbyopia) that made wearing thick glasses mandatory. "During my fifth week on StemEnhance® ," she relates, "I took off my glasses for a moment while driving, and I was shocked that I could see the license plates on cars in front of me. Before StemEnhance® , I would not have been able to see the cars from that distance, I am so nearsighted. Since then I have noticed continual improvement in my vision. I check myself daily, and every day I am seeing better and better!"


Connie E.:
Research shows that 3.2 million people in the United States suffer the discomfort of chronic dry eye syndrome. Many of those are women who have gone through menopause, and who often try to alleviate the awful discomfort with eye drops, saline spritzing and supplements with essential fatty acids. Connie knows all about this, because she has suffered for a long time with chronic dry eyes.

"I felt I had a future of eye discomfort and continual spritzing," Connie says, "but then I heard about StemEnhance® and decided to try it. I felt I had nothing to lose." Understanding that StemEnhance® increases stem cell production and migration to places in the body that need renewal, Connie began takng two capsules in the morning and two at night. Within four weeks, she was amazed to discover that she could open her eyes in the morning without spritzing them, and she no longer had to wake in the middle of the night to relieve her discomfort with eye drops. As she continues to use StemEnhance® , Connie's chronic dry eye is mostly just a memory, and she has noticed some other positive changes: She seems to be able to see a lot better, and those "sugar numbers" are now maintaining normal levels. Connie credits StemEnhance® with improving her quality of life. "I have not changed anything else in my life to make these things happen. My life is better because of StemEnhance® !"


Jim P.:

By the beginning of this year, life had become very difficult for Jim. He was in a nursing home, nourished through a feeding tube so he would not aspirate his food -- and he was unable to walk more than a few feet. Jim knew that he faced a continual disintegration of his quality of life.

A friend mentioned that Jim might want to try StemEnhance® . "It may help you," she suggested. Still unable to swallow, Jim had StemEnhance® added to his feeding tube solution, the contents of one capsule every six hours. Even before the capsules from that first bottle were gone, Jim said, "I think I feel different." He continued taking StemEnhance® , increasing his dosage to two capsules every six hours, and his physical condition continued to improve. Within four months, his swallowing reflex had returned, the feeding tube was gone, and Jim was eating solid food again... for the first time in months!

And the news keeps getting better: Before StemEnhance® , Jim had to use a mechanical lift to give him any mobility at all, he suffered uncontrollable tremors, and his condition affected his speech so that he was very difficult to understand. Things have really changed in only a few months, as Jim continues to take StemEnhance® , now four a day. Many of his health challenges seem to be fading away. Nowadays, Jim can get up from the table without assistance after eating a normal meal and engaging in pleasant conversation, and go for a one-mile walk. What a dramatic turnaround in his quality of life! "Oh, I still get tired sometimes," Jim confesses, "but I've gained back fifty pounds, and everything is so much better for me now. StemEnhance® has given me my life back!"

Double-Blind Study

Double-Blind Randomized Placebo-Controlled Study of the Effect of StemEnhance on Bone Marrow Stem Cell Mobilization by Christian Drapeau, MSc.

Aim of the study

A double-blinded, randomized, placebo-controlled study on human subjects was conducted on the effect of various AFA extracts on the numbers of circulating stem cells.

Methods

Consumables
Volunteers were fed a blend of two AFA extracts (StemEnhance - SE), and a placebo (Ctrl).

Volunteers
A total of 15 healthy volunteers were selected using the following exclusion criteria:

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Under 20 or over 65 years of age

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Pregnancy

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Severe asthma and allergies requiring daily medication

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Any known chronic illness or previous/current venereal disease

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Frequent recreational drug use

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Impaired digestive function (including previous major gastrointestinal surgery).

Upon arrival, the volunteers were seated in quiet areas and instructed to remain quiescent, comfortably sitting in a chair, for one hour. Immediately after drawing the baseline sample, a consumable was provided. The volunteers were instructed to remain quiescent for the whole duration of the experiment. Blood samples were later drawn 30, 60 and 120 minutes after ingestion of the consumable.

Assessment of circulating stem cells

At each time point, 5 ml blood was drawn into heparin, and 2 ml blood was drawn into EDTA. One sample was used to perform a complete blood count (CBC) while the other sample was prepared for immunostaining (CD34, CD45 and CD14) and flow cytometry. Data are expressed as mean +/- standard error.

Results
Consumption of SE led to an increase in the number of circulating CD34+ cells, while consumption of the placebo did not lead to any statistically significant effect.

Since the overall time for the absorption of bioactive compounds, delivery to target organs, and the generation a quantifiable physiological response may be different depending on each volunteers overall physiology, we calculated the maximum response of SE at any one point in time, within 60 minutes of consumption. We found a 24 +/- 5 % increase (median = 27%) in the number of circulating stem cells with SE. If we include data obtained during a dose study performed in May 2005, the average maximum response raises to 30 +/- 6%.

 

Figure 1. Time course of the number of CD34+ cells in peripheral blood after consumption (arrow) of SE and placebo (Crtl). Data are expressed as % of starting value. Bars express standard error.

Discussion
This study confirmed that SE is effective at supporting the release of stem cells from the bone marrow, increasing the number of circulating stem cells (CD34+ cells). The data collected show that SE increases the number of circulating stem cells by up to 30%.

Physiological relevance of the observed stem cell mobilization
In this study the average number of lymphocytes was 1,978 per �L and the average proportion of CD34+ cells at time 0 was 0.12%, for an average number of circulating CD34+ cells of 2.4 per �L. An increase of 25% to 30%, as seen in this study, translates to an average increase of 0.7 stem cells per �L, i.e. from 2.4 to 3.1 stem cells per �L. Assuming 5.0 liters of blood, this corresponds to approximately 3.5 million new circulating stem cells. The novelty of the concept of using endogenous release of bone marrow stem cells to support optimal health is paralleled by a scarcity of data linking the magnitude of mobilization with physiological relevance. Nevertheless, data exist to estimate the physiological relevance of putting into circulation 3.5 million new stem cells. Based on various studies (Orlic et al. 2001; Bodine et al., 1994; Bodine et al. 1993; Vandelverde et al., 2005; Valgimigli et al., 2005) one can estimate that one gram of StemEnhance can lead to potentially of up to a few billion somatic cells in target tissues. Therefore the average increase of 25% to 30% obtained with SE in this study is likely to have physiological relevance.

References
Bodine DM, Seidel NE, Gale MS, Nienhuis AW, and. (1994) Efficient Retrovirus Transduction of Mouse Pluripotent Hematopoietic Stem Cells Mobilized Into the Peripheral Blood by Treatment With Granulocyte Colony-Stimulating Factor and Stem Cell Factor. Blood, 84(5): 1482-1491.

Bodine DM, Seidel NE, Zsebo KM, and Orlic D. (1993) In Vivo Administration of Stem Cell Factor to Mice Increases the Absolute Number of Pluripotent Hematopoietic Stem Cells. Blood, 82(2): 445-455.

Orlic D, Kajstura J, Chimenti S, Bodine DM, Leri A. & Anversa P. (2003) Bone marrow stem cells regenerate infarcted myocardium. Pediatr Transplantation 7 (Suppl. 3): 86�88.

Orlic D, Kajstura J, Chimenti S, Limana F, Jakoniuk I, Quaini F, Nadal-Ginard B, Bodine DM, Leri A. & Anversa P. (2001) Mobilized bone marrow cells repair the infracted heart, improving function and survival. PNAS 98(18):10344�10349.

Valgimigli M, Rigolin GM, Cittanti C, Malagutti P, Curello S, Percoco G, Bugli AM, Porta MD, Bragotti LZ, Ansani L, Mauro E, Lanfranchi A, Giganti M, Feggi L, Castoldi G, Ferrari R. (2005) Use of granulocyte-colony stimulating factor during acute myocardial infarction to enhance bone marrow stem cell mobilization in humans: clinical and angiographic safety profile. Eur Heart J. Apr 28. Epub.

Vandervelde S, van Luyn MJ, Tio RA, Harmsen MC. (2005) Signaling factors in stem cell-mediated repair of infarcted myocardium. J Mol Cell Cardiol. Jun 28. Epub.

Stem Enhance Product Information

The benefits of healthy stem cell support includes enhancing optimal wellness and can fight effects of aging. Healthy stem cells can help you feel stronger and more vigorous as you advance into retirement years.
Let's face it, people today regardless of their age want to enjoy good health, fell and look better, and be able to do more play and hard work without tiring out to fast.
Stem Enhance is the all natural supplement that helps support the natural release of adult stem cells.

What is Stem Enhance?
A new breakthrough health supplement ed StemEnhance is a natural botanical extract that supports wellness by helping your body maintain healthy stem cell physiology. It is the very first supplement on the market from the latest hot phytoceutical product category ed "stem cell enhancer's".

What are stem cell enhancer's?

According to recent scientific developments, show that stem cells derived from the bone marrow, travel throughout the body, and act to support optimal organ and tissue function. Stem cell enhancers supplements are products that support the natural role of releasing adult stem cells.

Why do I need to try StemEnhance?

With advancing age, the number and quality of stem cells that circulate in your body gradually decrease, leaving your body more susceptible to injury and other age-related health challenges.

Just as antioxidants are important to protect your cells from "free radical" damage, stem cell enhancers are equally important to support your stem cells in maintaining proper organ and tissue functioning in your body.

Is StemEnhance scientifically studied?
Yes. Several clinical studies have been conducted on the product, in addition to several in-vitro trials.

How does Stem Enhance Work?
When you take two capsules, the ingredients help to support the release of stem cells from the bone marrow into the bloodstream. Through a natural process, those stem cells then travel to areas of the body where they are most needed.

What are stem cells?
Stem cells can be thought of as "master" cells. You've probably heard about the controversy of embryonic stem cells in the news. Stem cells are found in human embryos, but are also found in adult tissue.

Adult stem cells are most abundantly found in bone marrow. Stem cells circulate and function to replace dysfunctional cells, thus fulfilling the natural process of maintaining optimal health. StemEnhance supports the release of adult stem cells from bone marrow into circulation.

The recent advances in stem cell research were listed as one of the most significant health-related stories in the past 25 years by CNN, second only to the complete mapping of the human genome.

Order your bottle of Stem Enhance Today

Recommended dose
One gram of StemEnhance triggers an average 25-30% increase in the number of circulating
stem cells. The effect lasts for a few hours. The recommended dosage is therefore 2 capsules
once or twice day, at least 6 hours apart.

Each bottle contains 60 vegetarian capsules of StemEnhance, which is 30 servings.

Description
StemEnhance is a blend of two compounds extracted from the cyanophyta Aphanizomenon
flos-aquae (AFA). These compounds are extracted using a proprietary process that utilizes no
chemicals or harsh agents. One extract, which contains an L-selectin ligand, supports the release of stem cells (CD34 cells) from the bone marrow. The other extract, a polysaccharide-rich fraction named MigratoseT,
may support the migration of stem cells out of the blood into tissues. Effectiveness of StemEnhance was demonstrated in a triple-blind study. Volunteers rested for one hour before establishing baseline levels. After the
first blood samples, volunteers were given StemEnhance or placebo. Thereafter, blood samples were taken at 30, 60 and 120 minutes after taking the consumables. The number of circulating stem cells was quantified
by analyzing the blood samples using Fluorescence-Activated Cell Sorting (FACS). Consumption of StemEnhance triggered a significant 25-30% increase in the number of circulating stem cells.